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Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells
We examined the roles of Notch1 signaling and its cross-talk with other signaling pathways, including p53 and phosphatidylinositol-3-kinase (PI3K)/Akt, in cadmium-induced cellular damage in HK-2 human renal proximal tubular epithelial cells. Following exposure to cadmium chloride (CdCl(2)), the leve...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454314/ https://www.ncbi.nlm.nih.gov/pubmed/25118938 http://dx.doi.org/10.1038/cddis.2014.339 |