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Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells

We examined the roles of Notch1 signaling and its cross-talk with other signaling pathways, including p53 and phosphatidylinositol-3-kinase (PI3K)/Akt, in cadmium-induced cellular damage in HK-2 human renal proximal tubular epithelial cells. Following exposure to cadmium chloride (CdCl(2)), the leve...

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Detalles Bibliográficos
Autores principales:	Fujiki, K, Inamura, H, Matsuoka, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454314/ https://www.ncbi.nlm.nih.gov/pubmed/25118938 http://dx.doi.org/10.1038/cddis.2014.339

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