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An unexpected role for caspase-2 in neuroblastoma

Caspase-2 has been implicated in various cellular functions, including cell death by apoptosis, oxidative stress response, maintenance of genomic stability and tumor suppression. The loss of the caspase-2 gene (Casp2) enhances oncogene-mediated tumorigenesis induced by E1A/Ras in athymic nude mice,...

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Detalles Bibliográficos
Autores principales: Dorstyn, L, Puccini, J, Nikolic, A, Shalini, S, Wilson, C H, Norris, M D, Haber, M, Kumar, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454317/
https://www.ncbi.nlm.nih.gov/pubmed/25144718
http://dx.doi.org/10.1038/cddis.2014.342