RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage

The receptor-interacting protein kinase 3 (RIP3) associates with RIP1 in a necrosome complex that can induce necroptosis, apoptosis, or cell proliferation. We analyzed the expression of RIP1 and RIP3 in CD34+ leukemia cells from a cohort of patients with acute myeloid leukemia (AML) and CD34+ cells...

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Detalles Bibliográficos
Autores principales: Nugues, A-L, El Bouazzati, H, Hétuin, D, Berthon, C, Loyens, A, Bertrand, E, Jouy, N, Idziorek, T, Quesnel, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454320/
https://www.ncbi.nlm.nih.gov/pubmed/25144719
http://dx.doi.org/10.1038/cddis.2014.347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454320/
https://www.ncbi.nlm.nih.gov/pubmed/25144719
http://dx.doi.org/10.1038/cddis.2014.347

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