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Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer's disease
Increasing evidence has shown the aberrant expression of inflammasome-related proteins in Alzheimer's disease (AD) brain; these proteins, including NLRP1 inflammasome, are implicated in the execution of inflammatory response and pyroptotic death. Although current data are associated NLRP1 genet...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454321/ https://www.ncbi.nlm.nih.gov/pubmed/25144717 http://dx.doi.org/10.1038/cddis.2014.348 |