Compartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2

Localized in the plasma membrane, death domain-containing TNF-related apoptosis-inducing ligand (TRAIL) receptors, TRAIL-R1 and TRAIL-R2, induce apoptosis and non-apoptotic signaling when crosslinked by the ligand TRAIL or by agonistic receptor-specific antibodies. Recently, an increasing body of ev...

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Detalles Bibliográficos
Autores principales: Bertsch, U, Röder, C, Kalthoff, H, Trauzold, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454323/
https://www.ncbi.nlm.nih.gov/pubmed/25165876
http://dx.doi.org/10.1038/cddis.2014.351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454323/
https://www.ncbi.nlm.nih.gov/pubmed/25165876
http://dx.doi.org/10.1038/cddis.2014.351

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