Cargando…

Compartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2

Localized in the plasma membrane, death domain-containing TNF-related apoptosis-inducing ligand (TRAIL) receptors, TRAIL-R1 and TRAIL-R2, induce apoptosis and non-apoptotic signaling when crosslinked by the ligand TRAIL or by agonistic receptor-specific antibodies. Recently, an increasing body of ev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bertsch, U, Röder, C, Kalthoff, H, Trauzold, A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454323/ https://www.ncbi.nlm.nih.gov/pubmed/25165876 http://dx.doi.org/10.1038/cddis.2014.351

Ejemplares similares

TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors
por: Mert, Ufuk, et al.
Publicado: (2019)

Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC
por: Gundlach, Jan-Paul, et al.
Publicado: (2018)

TRAIL-β and TRAIL-γ: two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential
por: Krieg, A, et al.
Publicado: (2003)

Targeting Death Receptor TRAIL-R2 by Chalcones for TRAIL-Induced Apoptosis in Cancer Cells
por: Szliszka, Ewelina, et al.
Publicado: (2012)

Should We Keep Walking along the Trail for Pancreatic Cancer Treatment? Revisiting TNF-Related Apoptosis-Inducing Ligand for Anticancer Therapy
por: Kretz, Anna-Laura, et al.
Publicado: (2018)

TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells
por: Voigt, Susann, et al.
Publicado: (2014)

Periplasmic Expression of TNF Related Apoptosis Inducing Ligand (TRAIL) in E.coli
por: Tavallaei, Omid, et al.
Publicado: (2015)

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death
por: Dufour, Florent, et al.
Publicado: (2017)

TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors
por: Yang, Xi, et al.
Publicado: (2017)

Expression of TNF-related apoptosis-inducing ligand (TRAIL) in keratinocytes mediates apoptotic cell death in allogenic T cells
por: Reimers, Kerstin, et al.
Publicado: (2009)

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
por: Dufour, Florent, et al.
Publicado: (2016)

Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes
por: Zoller, Verena, et al.
Publicado: (2017)

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
por: Estornes, Yann, et al.
Publicado: (2018)

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes
por: Staniek, Julian, et al.
Publicado: (2019)

Endogenous TRAIL-R4 critically impacts apoptotic and non-apoptotic TRAIL-induced signaling in cancer cells
por: Rambow, Anna-Christina, et al.
Publicado: (2022)

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation
por: McGrath, Emmet E., et al.
Publicado: (2011)

CD95L Inhibition Impacts Gemcitabine-Mediated Effects and Non-Apoptotic Signaling of TNF-α and TRAIL in Pancreatic Tumor Cells
por: Rashid, Khalid, et al.
Publicado: (2021)

Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family
por: Degli-Esposti, Mariapia A., et al.
Publicado: (1997)

H-Ras regulation of TRAIL death receptor mediated apoptosis
por: Chen, Jun-Jie, et al.
Publicado: (2014)

Prognostic Value of TNF-Related Apoptosis Inducing Ligand (TRAIL) in Acute Coronary Syndrome Patients
por: Osmancik, Pavel, et al.
Publicado: (2013)

Assessment of concentrations of sTRAIL ligand and its receptors sTRAIL-R1 and sTRAIL-R2 – markers monitoring the course of the extrinsic pathway of apoptosis induction: potential application in ovarian cancer diagnostics
por: Mielczarek-Palacz, Aleksandra, et al.
Publicado: (2015)

Therapeutic targeting of TRAIL death receptors
por: Di Cristofano, Francesca, et al.
Publicado: (2023)

Lipid Nanoparticles Decorated with TNF-Related Aptosis-Inducing Ligand (TRAIL) Are More Cytotoxic than Soluble Recombinant TRAIL in Sarcoma
por: Gallego-Lleyda, Ana, et al.
Publicado: (2018)

Is there any correlation between TNF-related apoptosis-inducing ligand (TRAIL) genetic variants and breast cancer?
por: Yildiz, Yemliha, et al.
Publicado: (2010)

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
por: Keuper, M, et al.
Publicado: (2013)

TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice
por: Steinwede, Kathrin, et al.
Publicado: (2012)

The Combination of TRAIL Treatment and Cancer Cell Selective Expression of TRAIL-Death Receptor DR4 Induces Cell Death in TRAIL-Resistant Cancer Cells
por: Choi, Eunah, et al.
Publicado: (2006)

The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Receptors 1 and 2 Co-Regulate Apoptotic Signaling Capacity
por: Neumann, Simon, et al.
Publicado: (2012)

TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill
por: Mohr, Andrea, et al.
Publicado: (2015)

TRAIL/TRAIL Receptor System and Susceptibility to Multiple Sclerosis
por: López-Gómez, Carlos, et al.
Publicado: (2011)

Tristetraprolin Posttranscriptionally Downregulates TRAIL Death Receptors
por: Lee, Won Hyeok, et al.
Publicado: (2020)

Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction
por: Hendriks, Djoke, et al.
Publicado: (2016)

Hydrogen Peroxide Upregulates TNF-Related Apoptosis-Inducing Ligand (TRAIL) Expression in Human Astroglial Cells, and Augments Apoptosis of T Cells
por: Kwon, Daeho, et al.
Publicado: (2006)

Characterization of the Role of Tumor Necrosis Factor Apoptosis Inducing Ligand (TRAIL) in Spermatogenesis through the Evaluation of Trail Gene-Deficient Mice
por: Lin, Yi-Chen, et al.
Publicado: (2014)

The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells
por: Legler, Karen, et al.
Publicado: (2018)

Following the fat trail to death
por: Williams, Ruth
Publicado: (2009)

The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells
por: Ryu, Sunhyo, et al.
Publicado: (2018)

TRAF-6 Dependent Signaling Pathway Is Essential for TNF-Related Apoptosis-Inducing Ligand (TRAIL) Induces Osteoclast Differentiation
por: Yen, Men-Luh, et al.
Publicado: (2012)

Blockade of Death Ligand TRAIL Inhibits Renal Ischemia Reperfusion Injury
por: Adachi, Takaomi, et al.
Publicado: (2013)

TRAIL-Induced Apoptosis in TRAIL-Resistant Breast Carcinoma Through Quercetin Cotreatment
por: Manouchehri, Jasmine M, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7npq18jrm3c46oi18pkomptnf6