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Dock3 protects myelin in the cuprizone model for demyelination

Dedicator of cytokinesis 3 (Dock3) belongs to an atypical family of the guanine nucleotide exchange factors. It is predominantly expressed in the neural tissues and causes cellular morphological changes by activating the small GTPase Rac1. We previously reported that Dock3 overexpression protects re...

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Detalles Bibliográficos
Autores principales: Namekata, K, Kimura, A, Harada, C, Yoshida, H, Matsumoto, Y, Harada, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454328/
https://www.ncbi.nlm.nih.gov/pubmed/25165881
http://dx.doi.org/10.1038/cddis.2014.357