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Mutation Burden of Rare Variants in Schizophrenia Candidate Genes

BACKGROUND: Schizophrenia (SCZ) is a very heterogeneous disease that affects approximately 1% of the general population. Recently, the genetic complexity thought to underlie this condition was further supported by three independent studies that identified an increased number of damaging de novo muta...

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Detalles Bibliográficos
Autores principales: Girard, Simon L., Dion, Patrick A., Bourassa, Cynthia V., Geoffroy, Steve, Lachance-Touchette, Pamela, Barhdadi, Amina, Langlois, Mathieu, Joober, Ridha, Krebs, Marie-Odile, Dubé, Marie-Pierre, Rouleau, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454531/
https://www.ncbi.nlm.nih.gov/pubmed/26039597
http://dx.doi.org/10.1371/journal.pone.0128988