Cargando…
Mutation Burden of Rare Variants in Schizophrenia Candidate Genes
BACKGROUND: Schizophrenia (SCZ) is a very heterogeneous disease that affects approximately 1% of the general population. Recently, the genetic complexity thought to underlie this condition was further supported by three independent studies that identified an increased number of damaging de novo muta...
Autores principales: | Girard, Simon L., Dion, Patrick A., Bourassa, Cynthia V., Geoffroy, Steve, Lachance-Touchette, Pamela, Barhdadi, Amina, Langlois, Mathieu, Joober, Ridha, Krebs, Marie-Odile, Dubé, Marie-Pierre, Rouleau, Guy A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454531/ https://www.ncbi.nlm.nih.gov/pubmed/26039597 http://dx.doi.org/10.1371/journal.pone.0128988 |
Ejemplares similares
-
Investigation of rare variants in LRP1, KPNA1, ALS2CL and ZNF480 genes in schizophrenia patients reflects genetic heterogeneity of the disease
por: Jouan, Loubna, et al.
Publicado: (2013) -
Association study of the trinucleotide repeat polymorphism within SMARCA2 and schizophrenia
por: Sengupta, Sarojini, et al.
Publicado: (2006) -
De novo variants in sporadic cases of childhood onset schizophrenia
por: Ambalavanan, Amirthagowri, et al.
Publicado: (2016) -
Paternal Age Explains a Major Portion of De Novo Germline Mutation Rate Variability in Healthy Individuals
por: Girard, Simon L., et al.
Publicado: (2016) -
Two-stage strategies to detect gene × gene interactions in case-control data
por: Barhdadi, Amina, et al.
Publicado: (2007)