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Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype

Even with identification of multiple causal genetic variants for common human diseases, understanding the molecular processes mediating the causal variants’ effect on the disease remains a challenge. This understanding is crucial for the development of therapeutic strategies to prevent and treat dis...

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Detalles Bibliográficos
Autores principales: Gupta, Saumya, Radhakrishnan, Aparna, Raharja-Liu, Pandu, Lin, Gen, Steinmetz, Lars M., Gagneur, Julien, Sinha, Himanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454590/
https://www.ncbi.nlm.nih.gov/pubmed/26039065
http://dx.doi.org/10.1371/journal.pgen.1005195