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Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype
Even with identification of multiple causal genetic variants for common human diseases, understanding the molecular processes mediating the causal variants’ effect on the disease remains a challenge. This understanding is crucial for the development of therapeutic strategies to prevent and treat dis...
Autores principales: | Gupta, Saumya, Radhakrishnan, Aparna, Raharja-Liu, Pandu, Lin, Gen, Steinmetz, Lars M., Gagneur, Julien, Sinha, Himanshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454590/ https://www.ncbi.nlm.nih.gov/pubmed/26039065 http://dx.doi.org/10.1371/journal.pgen.1005195 |
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