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MEK and TGF-beta Inhibition Promotes Reprogramming without the Use of Transcription Factor

The possibility of replacing the originally discovered and widely used DNA reprogramming transcription factors is stimulating enormous effort to identify more effective compounds that would not alter the genetic information. Here, we describe the generation of induced pluripotent stem cells (iPSc) f...

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Detalles Bibliográficos
Autores principales: Vrbsky, Jan, Tereh, Tamas, Kyrylenko, Sergiy, Dvorak, Petr, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454598/
https://www.ncbi.nlm.nih.gov/pubmed/26039048
http://dx.doi.org/10.1371/journal.pone.0127739