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MEK and TGF-beta Inhibition Promotes Reprogramming without the Use of Transcription Factor
The possibility of replacing the originally discovered and widely used DNA reprogramming transcription factors is stimulating enormous effort to identify more effective compounds that would not alter the genetic information. Here, we describe the generation of induced pluripotent stem cells (iPSc) f...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454598/ https://www.ncbi.nlm.nih.gov/pubmed/26039048 http://dx.doi.org/10.1371/journal.pone.0127739 |