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The Role of Heparanase in Pulmonary Cell Recruitment in Response to an Allergic but Not Non-Allergic Stimulus

Heparanase is an endo-β-glucuronidase that specifically cleaves heparan sulfate proteoglycans in the extracellular matrix. Expression of this enzyme is increased in several pathological conditions including inflammation. We have investigated the role of heparanase in pulmonary inflammation in the co...

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Detalles Bibliográficos
Autores principales: Morris, Abigail, Wang, Bo, Waern, Ida, Venkatasamy, Radhakrishnan, Page, Clive, Schmidt, Eric P., Wernersson, Sara, Li, Jin-Ping, Spina, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454641/
https://www.ncbi.nlm.nih.gov/pubmed/26039697
http://dx.doi.org/10.1371/journal.pone.0127032