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Activation of C3a receptor is required in cigarette smoke-mediated emphysema

Exposure to cigarette smoke can initiate sterile inflammatory responses in the lung and activate myeloid dendritic cells (mDCs) that induce differentiation of T helper type 1 (Th1) and Th17 cells in the emphysematous lungs. Consumption of complement proteins increases in acute inflammation, but the...

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Detalles Bibliográficos
Autores principales: Yuan, Xiaoyi, Shan, Ming, You, Ran, Frazier, Michael V., Hong, Monica Jeongsoo, Wetsel, Rick A., Drouin, Scott, Seryshev, Alexander, MD, Li-zhen Song, Cornwell, Lorraine, Rossen, Roger D, Corry, David B., Kheradmand, Farrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454642/
https://www.ncbi.nlm.nih.gov/pubmed/25465103
http://dx.doi.org/10.1038/mi.2014.118