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Nicotinic Acetylcholine Receptor (nAChR) Dependent Chorda Tympani Taste Nerve Responses to Nicotine, Ethanol and Acetylcholine

Nicotine elicits bitter taste by activating TRPM5-dependent and TRPM5-independent but neuronal nAChR-dependent pathways. The nAChRs represent common targets at which acetylcholine, nicotine and ethanol functionally interact in the central nervous system. Here, we investigated if the nAChRs also repr...

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Detalles Bibliográficos
Autores principales: Ren, Zuo Jun, Mummalaneni, Shobha, Qian, Jie, Baumgarten, Clive M., DeSimone, John A., Lyall, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454666/
https://www.ncbi.nlm.nih.gov/pubmed/26039516
http://dx.doi.org/10.1371/journal.pone.0127936