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Characterization of a Large Panel of Rabbit Monoclonal Antibodies against HIV-1 gp120 and Isolation of Novel Neutralizing Antibodies against the V3 Loop

We recently reported the induction of potent, cross-clade neutralizing antibodies (nAbs) against Human Immunodeficiency Virus type-1 (HIV-1) in rabbits using gp120 based on an M-group consensus sequence. To better characterize these antibodies, 93 hybridomas were generated, which represent the large...

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Detalles Bibliográficos
Autores principales: Qin, Yali, Banerjee, Saikat, Agrawal, Aditi, Shi, Heliang, Banasik, Marisa, Lin, Feng, Rohl, Kari, LaBranche, Celia, Montefiori, David C., Cho, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454676/
https://www.ncbi.nlm.nih.gov/pubmed/26039641
http://dx.doi.org/10.1371/journal.pone.0128823