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Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors

BACKGROUND: Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase...

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Detalles Bibliográficos
Autores principales: Fajtová, Pavla, Štefanić, Saša, Hradilek, Martin, Dvořák, Jan, Vondrášek, Jiří, Jílková, Adéla, Ulrychová, Lenka, McKerrow, James H., Caffrey, Conor R., Mareš, Michael, Horn, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454677/
https://www.ncbi.nlm.nih.gov/pubmed/26039195
http://dx.doi.org/10.1371/journal.pntd.0003827