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Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors
BACKGROUND: Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase...
Autores principales: | Fajtová, Pavla, Štefanić, Saša, Hradilek, Martin, Dvořák, Jan, Vondrášek, Jiří, Jílková, Adéla, Ulrychová, Lenka, McKerrow, James H., Caffrey, Conor R., Mareš, Michael, Horn, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454677/ https://www.ncbi.nlm.nih.gov/pubmed/26039195 http://dx.doi.org/10.1371/journal.pntd.0003827 |
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