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Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

Mitochondria play a vital role in embryo development. They are the principal site of energy production and have various other critical cellular functions. Despite the importance of this organelle, little is known about the extent of variation in mitochondrial DNA (mtDNA) between individual human emb...

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Detalles Bibliográficos
Autores principales: Fragouli, Elpida, Spath, Katharina, Alfarawati, Samer, Kaper, Fiona, Craig, Andrew, Michel, Claude-Edouard, Kokocinski, Felix, Cohen, Jacques, Munne, Santiago, Wells, Dagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454688/
https://www.ncbi.nlm.nih.gov/pubmed/26039092
http://dx.doi.org/10.1371/journal.pgen.1005241