High OCT4 and Low p16(INK4A) Expressions Determine In Vitro Lifespan of Mesenchymal Stem Cells

After long-term culture, mesenchymal stem cells alter their biological properties and enter into a state of replicative senescence. Although several classical biomarkers have been used for quantitative assessment of cellular senescence, no hallmark has been proven completely unique to the senescent...

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Detalles Bibliográficos
Autores principales: Piccinato, Carla A., Sertie, Andrea L., Torres, Natália, Ferretti, Mario, Antonioli, Eliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454755/
https://www.ncbi.nlm.nih.gov/pubmed/26089914
http://dx.doi.org/10.1155/2015/369828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454755/
https://www.ncbi.nlm.nih.gov/pubmed/26089914
http://dx.doi.org/10.1155/2015/369828

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