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Polarized Cell Motility Induces Hydrogen Peroxide to Inhibit Cofilin via Cysteine Oxidation

Mesenchymal cell motility is driven by polarized actin polymerization [1]. Signals at the leading edge recruit actin polymerization machinery to promote membrane protrusion, while matrix adhesion generates tractive force to propel forward movement. To work effectively, cell motility is regulated by...

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Detalles Bibliográficos
Autores principales: Cameron, Jenifer M., Gabrielsen, Mads, Chim, Ya Hua, Munro, June, McGhee, Ewan J., Sumpton, David, Eaton, Philip, Anderson, Kurt I., Yin, Huabing, Olson, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454775/
https://www.ncbi.nlm.nih.gov/pubmed/25981793
http://dx.doi.org/10.1016/j.cub.2015.04.020