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Transcriptional Regulation via Nuclear Receptor Crosstalk Required for the Drosophila Circadian Clock
Circadian clocks in large part rely on transcriptional feedback loops. At the core of the clock machinery, the transcriptional activators CLOCK/BMAL1 (in mammals) and CLOCK/CYCLE (CLK/CYC) (in Drosophila) drive the expression of the period (per) family genes. The PER-containing complexes inhibit the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454776/ https://www.ncbi.nlm.nih.gov/pubmed/26004759 http://dx.doi.org/10.1016/j.cub.2015.04.017 |