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Transcriptional Regulation via Nuclear Receptor Crosstalk Required for the Drosophila Circadian Clock

Circadian clocks in large part rely on transcriptional feedback loops. At the core of the clock machinery, the transcriptional activators CLOCK/BMAL1 (in mammals) and CLOCK/CYCLE (CLK/CYC) (in Drosophila) drive the expression of the period (per) family genes. The PER-containing complexes inhibit the...

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Detalles Bibliográficos
Autores principales:	Jaumouillé, Edouard, Machado Almeida, Pedro, Stähli, Patrick, Koch, Rafael, Nagoshi, Emi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454776/ https://www.ncbi.nlm.nih.gov/pubmed/26004759 http://dx.doi.org/10.1016/j.cub.2015.04.017

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