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The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. However, the mechanism by which they are recognized and targeted to the exosome is not fully understood. Here we report that the MTREC complex, which has recently been shown to promote degradation of meiotic mRNAs and r...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Zhu, Jianguo, Schermann, Géza, Ohle, Corina, Bendrin, Katja, Sugioka-Sugiyama, Rie, Sugiyama, Tomoyasu, Fischer, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455066/
https://www.ncbi.nlm.nih.gov/pubmed/25989903
http://dx.doi.org/10.1038/ncomms8050