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Photoswitchable fatty acids enable optical control of TRPV1

Fatty acids (FAs) are not only essential components of cellular energy storage and structure, but play crucial roles in signalling. Here we present a toolkit of photoswitchable FA analogues (FAAzos) that incorporate an azobenzene photoswitch along the FA chain. By modifying the FAAzos to resemble ca...

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Detalles Bibliográficos
Autores principales: Frank, James Allen, Moroni, Mirko, Moshourab, Rabih, Sumser, Martin, Lewin, Gary R., Trauner, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455067/
https://www.ncbi.nlm.nih.gov/pubmed/25997690
http://dx.doi.org/10.1038/ncomms8118