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Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition

Biofunctionalization with siRNA targeting the key negative modulators of bone turnover involved in the molecular mechanism of osteoporosis, such as casein kinase-2 interacting protein-1 (Ckip-1), may lead to enhanced Ti osseointegration in the osteoporotic condition. In this study, even siRNA loadin...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Wu, Kaimin, Song, Wen, Xu, Haiyan, An, Ran, Zhao, Lingzhou, Liu, Bin, Zhang, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455222/
https://www.ncbi.nlm.nih.gov/pubmed/26040545
http://dx.doi.org/10.1038/srep10860