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Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition
Biofunctionalization with siRNA targeting the key negative modulators of bone turnover involved in the molecular mechanism of osteoporosis, such as casein kinase-2 interacting protein-1 (Ckip-1), may lead to enhanced Ti osseointegration in the osteoporotic condition. In this study, even siRNA loadin...
Autores principales: | Zhang, Li, Wu, Kaimin, Song, Wen, Xu, Haiyan, An, Ran, Zhao, Lingzhou, Liu, Bin, Zhang, Yumei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455222/ https://www.ncbi.nlm.nih.gov/pubmed/26040545 http://dx.doi.org/10.1038/srep10860 |
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