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SUMOylation of xeroderma pigmentosum group C protein regulates DNA damage recognition during nucleotide excision repair
The xeroderma pigmentosum group C (XPC) protein complex is a key factor that detects DNA damage and initiates nucleotide excision repair (NER) in mammalian cells. Although biochemical and structural studies have elucidated the interaction of XPC with damaged DNA, the mechanism of its regulation in v...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455304/ https://www.ncbi.nlm.nih.gov/pubmed/26042670 http://dx.doi.org/10.1038/srep10984 |