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The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells

BACKGROUND: Urothelial carcinoma (UC) is the fifth most common cancer in the developed world. Delineation of differentiation subtypes in UC highlighted the importance of aberrant differentiation. Understanding underlying mechanisms may facilitate diagnosis and development of efficient therapy strate...

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Detalles Bibliográficos
Autores principales: Heubach, Judith, Monsior, Juliana, Deenen, René, Niegisch, Günter, Szarvas, Tibor, Niedworok, Christian, Schulz, Wolfgang Arthur, Hoffmann, Michèle Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455698/
https://www.ncbi.nlm.nih.gov/pubmed/25994132
http://dx.doi.org/10.1186/s12943-015-0371-8