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Aluminium-phthalocyanine chloride nanoemulsions for anticancer photodynamic therapy: Development and in vitro activity against monolayers and spheroids of human mammary adenocarcinoma MCF-7 cells

BACKGROUND: Photodynamic therapy (PDT) combines light, molecular oxygen and a photosensitizer to induce oxidative stress in target cells. Certain hydrophobic photosensitizers, such as aluminium-phthalocyanine chloride (AlPc), have significant potential for antitumor PDT applications. However, hydrop...

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Detalles Bibliográficos
Autores principales: Muehlmann, Luis Alexandre, Rodrigues, Mosar Corrêa, Longo, João Paulo Figueiró, Garcia, Mônica Pereira, Py-Daniel, Karen Rapp, Veloso, Aline Bessa, de Souza, Paulo Eduardo Narciso, da Silva, Sebastião William, Azevedo, Ricardo Bentes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455699/
https://www.ncbi.nlm.nih.gov/pubmed/25966866
http://dx.doi.org/10.1186/s12951-015-0095-3