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The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated α(2)M

BACKGROUND: Emerging data have suggested that cell surface GRP78 is a multifunctional receptor and has been linked to proliferative and antiapoptotic signaling cascades. Activated α(2−)macroglobin (α(2)M*) is a natural circulating ligand of cell surface GRP78. Association of cell surface GRP78 with...

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Detalles Bibliográficos
Autores principales: Zhao, Song, Li, Hongdan, Wang, Qingjun, Su, Chang, Wang, Guan, Song, Huijuan, Zhao, Liang, Luan, Zhidong, Su, Rongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455704/
https://www.ncbi.nlm.nih.gov/pubmed/25958313
http://dx.doi.org/10.1186/s12885-015-1401-z