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mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia
Chronic pain is a major public health problem with limited treatment options. Opioids remain a routine treatment for chronic pain, but extended exposure to opioid therapy can produce opioid tolerance and hyperalgesia. Although the mechanisms underlying chronic pain, opioid-induced tolerance, and opi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455918/ https://www.ncbi.nlm.nih.gov/pubmed/26024835 http://dx.doi.org/10.1186/s12990-015-0030-5 |