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HIV infection and antiretroviral therapy lead to unfolded protein response activation

BACKGROUND: The unfolded protein response (UPR) is one of the pathways triggered to ensure quality control of the proteins assembled in the endoplasmic reticulum (ER) when cell homeostasis is compromised. This mechanism is primarily composed of three transmembrane proteins serving as stress sensors:...

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Detalles Bibliográficos
Autores principales: Borsa, Mariana, Ferreira, Pedro L. C., Petry, Andrea, Ferreira, Luiz G. E., Camargo, Maristela M., Bou-Habib, Dumith Chequer, Pinto, Aguinaldo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455982/
https://www.ncbi.nlm.nih.gov/pubmed/25976933
http://dx.doi.org/10.1186/s12985-015-0298-0