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The Na(+)/H(+) Exchanger-3 (NHE3) Activity Requires Ezrin Binding to Phosphoinositide and Its Phosphorylation

Na(+)/H(+) exchanger-3 (NHE3) plays an essential role in maintaining sodium and fluid homeostasis in the intestine and kidney epithelium. Thus, NHE3 is highly regulated and its function depends on binding to multiple regulatory proteins. Ezrin complexed with NHE3 affects its activity via not well-de...

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Detalles Bibliográficos
Autores principales: Babich, Victor, Di Sole, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455992/
https://www.ncbi.nlm.nih.gov/pubmed/26042733
http://dx.doi.org/10.1371/journal.pone.0129306