Repulsive Guidance Molecule is a structural bridge between Neogenin and Bone Morphogenetic Protein

Repulsive guidance molecules (RGMs) control crucial processes spanning cell motility, adhesion, immune cell regulation and systemic iron metabolism. RGMs signal via two fundamental signaling cascades: the Neogenin (NEO1) and the Bone Morphogenetic Protein (BMP) pathways. Here, we report crystal stru...

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Detalles Bibliográficos
Autores principales: Healey, Eleanor G., Bishop, Benjamin, Elegheert, Jonathan, Bell, Christian H., Padilla-Parra, Sergi, Siebold, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456160/
https://www.ncbi.nlm.nih.gov/pubmed/25938661
http://dx.doi.org/10.1038/nsmb.3016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456160/
https://www.ncbi.nlm.nih.gov/pubmed/25938661
http://dx.doi.org/10.1038/nsmb.3016

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