Cargando…
Repulsive Guidance Molecule is a structural bridge between Neogenin and Bone Morphogenetic Protein
Repulsive guidance molecules (RGMs) control crucial processes spanning cell motility, adhesion, immune cell regulation and systemic iron metabolism. RGMs signal via two fundamental signaling cascades: the Neogenin (NEO1) and the Bone Morphogenetic Protein (BMP) pathways. Here, we report crystal stru...
Autores principales: | Healey, Eleanor G., Bishop, Benjamin, Elegheert, Jonathan, Bell, Christian H., Padilla-Parra, Sergi, Siebold, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456160/ https://www.ncbi.nlm.nih.gov/pubmed/25938661 http://dx.doi.org/10.1038/nsmb.3016 |
Ejemplares similares
-
Identification of the Neogenin-Binding Site on the Repulsive Guidance Molecule A
por: Itokazu, Takahide, et al.
Publicado: (2012) -
Spatiotemporal Expression of Repulsive Guidance Molecules (RGMs) and Their Receptor Neogenin in the Mouse Brain
por: van den Heuvel, Dianne M. A., et al.
Publicado: (2013) -
Repulsive Guidance Molecule A Regulates Adult Neurogenesis Via the Neogenin Receptor
por: Isaksen, Toke Jost, et al.
Publicado: (2020) -
Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex
por: Malinauskas, Tomas, et al.
Publicado: (2020) -
Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs)
por: Wu, Qifang, et al.
Publicado: (2012)