Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

The AAA(+) ATPase Vps4 disassembles ESCRT-III and is essential for HIV-1 budding and other pathways. Vps4 is a paradigmatic member of a class of hexameric AAA(+) ATPases that disassemble protein complexes without degradation. To distinguish between local displacement versus global unfolding mechanis...

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Detalles Bibliográficos
Autores principales: Yang, Bei, Stjepanovic, Goran, Shen, Qingtao, Martin, Andreas, Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456219/
https://www.ncbi.nlm.nih.gov/pubmed/25938660
http://dx.doi.org/10.1038/nsmb.3015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456219/
https://www.ncbi.nlm.nih.gov/pubmed/25938660
http://dx.doi.org/10.1038/nsmb.3015

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