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Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation
The AAA(+) ATPase Vps4 disassembles ESCRT-III and is essential for HIV-1 budding and other pathways. Vps4 is a paradigmatic member of a class of hexameric AAA(+) ATPases that disassemble protein complexes without degradation. To distinguish between local displacement versus global unfolding mechanis...
Autores principales: | Yang, Bei, Stjepanovic, Goran, Shen, Qingtao, Martin, Andreas, Hurley, James H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456219/ https://www.ncbi.nlm.nih.gov/pubmed/25938660 http://dx.doi.org/10.1038/nsmb.3015 |
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