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Regulation of NF-κB Oscillation by Nuclear Transport: Mechanisms Determining the Persistency and Frequency of Oscillation

The activated transcription factor NF-κB shuttles between the cytoplasm and the nucleus resulting in the oscillation of nuclear NF-κB (NF-κB(n)). The oscillation pattern of NF-κB(n) is implicated in the regulation of gene expression profiles. Using computational models, we previously reported that s...

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Detalles Bibliográficos
Autores principales: Ohshima, Daisuke, Ichikawa, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456371/
https://www.ncbi.nlm.nih.gov/pubmed/26042739
http://dx.doi.org/10.1371/journal.pone.0127633