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The VEGF-Receptor Inhibitor Axitinib Impairs Dendritic Cell Phenotype and Function

Inhibitors of VEGF receptor (VEGFR) signaling such as sorafenib and sunitinib that are currently used in the treatment of malignant diseases have been shown to affect immunological responses by inhibition of the function of antigen presenting cells and T lymphocytes. The VEGFR-inhibitor axitinib has...

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Detalles Bibliográficos
Autores principales: Heine, Annkristin, Held, Stefanie Andrea Erika, Daecke, Solveig Nora, Riethausen, Kati, Kotthoff, Philipp, Flores, Chrystel, Kurts, Christian, Brossart, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456373/
https://www.ncbi.nlm.nih.gov/pubmed/26042424
http://dx.doi.org/10.1371/journal.pone.0128897