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The VEGF-Receptor Inhibitor Axitinib Impairs Dendritic Cell Phenotype and Function
Inhibitors of VEGF receptor (VEGFR) signaling such as sorafenib and sunitinib that are currently used in the treatment of malignant diseases have been shown to affect immunological responses by inhibition of the function of antigen presenting cells and T lymphocytes. The VEGFR-inhibitor axitinib has...
Autores principales: | Heine, Annkristin, Held, Stefanie Andrea Erika, Daecke, Solveig Nora, Riethausen, Kati, Kotthoff, Philipp, Flores, Chrystel, Kurts, Christian, Brossart, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456373/ https://www.ncbi.nlm.nih.gov/pubmed/26042424 http://dx.doi.org/10.1371/journal.pone.0128897 |
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