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Combinations of Kinase Inhibitors Protecting Myoblasts against Hypoxia

Cell-based therapies to treat skeletal muscle disease are limited by the poor survival of donor myoblasts, due in part to acute hypoxic stress. After confirming that the microenvironment of transplanted myoblasts is hypoxic, we screened a kinase inhibitor library in vitro and identified five kinase...

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Detalles Bibliográficos
Autores principales: Kang, Yunyi, Tierney, Matthew, Ong, Edison, Zhang, Linda, Piermarocchi, Carlo, Sacco, Alessandra, Paternostro, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456388/
https://www.ncbi.nlm.nih.gov/pubmed/26042811
http://dx.doi.org/10.1371/journal.pone.0126718