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Combinations of Kinase Inhibitors Protecting Myoblasts against Hypoxia
Cell-based therapies to treat skeletal muscle disease are limited by the poor survival of donor myoblasts, due in part to acute hypoxic stress. After confirming that the microenvironment of transplanted myoblasts is hypoxic, we screened a kinase inhibitor library in vitro and identified five kinase...
Autores principales: | Kang, Yunyi, Tierney, Matthew, Ong, Edison, Zhang, Linda, Piermarocchi, Carlo, Sacco, Alessandra, Paternostro, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456388/ https://www.ncbi.nlm.nih.gov/pubmed/26042811 http://dx.doi.org/10.1371/journal.pone.0126718 |
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