Substrate stereoselectivity of poly(Asp) hydrolase-1 capable of cleaving β-amide bonds as revealed by investigation of enzymatic hydrolysis of stereoisomeric β-tri(Asp)s

We previously reported that poly(Asp) hydrolase-1 (PahZ1(KP-2)) from Pedobacter sp. KP-2 selectively, but not completely, cleaved the amide bonds between β-Asp units in thermally synthesized poly(Asp) (tPAA). In the present study, the enzymatic hydrolysis of stereoisomeric β-tri(Asp)s by PahZ1(KP-2)...

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Detalles Bibliográficos
Autores principales: Hiraishi, Tomohiro, Abe, Hideki, Maeda, Mizuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456602/
https://www.ncbi.nlm.nih.gov/pubmed/26054734
http://dx.doi.org/10.1186/s13568-015-0118-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456602/
https://www.ncbi.nlm.nih.gov/pubmed/26054734
http://dx.doi.org/10.1186/s13568-015-0118-3

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