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RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice

BACKGROUND: Dose-dependent differential gene expression provides critical information required for regulatory decision-making. The lower costs associated with RNA-Seq have made it the preferred technology for transcriptomic analysis. However, concordance between RNA-Seq and microarray analyses in do...

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Detalles Bibliográficos
Autores principales: Nault, Rance, Fader, Kelly A, Zacharewski, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456707/
https://www.ncbi.nlm.nih.gov/pubmed/25958198
http://dx.doi.org/10.1186/s12864-015-1527-z