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Efficient in vitro generation of functional thymic epithelial progenitors from human embryonic stem cells

Thymic epithelial cells (TECs) are the major components of the thymic microenvironment for T cell development. TECs are derived from thymic epithelial progenitors (TEPs). It has been reported that human ESCs (hESCs) can be directed to differentiate into TEPs in vitro. However, the efficiency for the...

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Detalles Bibliográficos
Autores principales: Su, Min, Hu, Rong, Jin, Jingjun, Yan, Yuan, Song, Yinhong, Sullivan, Ryan, Lai, Laijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456731/
https://www.ncbi.nlm.nih.gov/pubmed/26044259
http://dx.doi.org/10.1038/srep09882