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ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells
BACKGROUND: Treatment of blast phase chronic myeloid leukemia (BP-CML) remains a challenge, and the median survival is less than 6 months. Because effective treatments are lacking, we studied tight targeting of blast crisis CML cells using adenoviral (Ad) vectors expressing a HSV-TK system under dua...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456766/ https://www.ncbi.nlm.nih.gov/pubmed/26017281 http://dx.doi.org/10.1186/s13046-015-0139-4 |