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ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells

BACKGROUND: Treatment of blast phase chronic myeloid leukemia (BP-CML) remains a challenge, and the median survival is less than 6 months. Because effective treatments are lacking, we studied tight targeting of blast crisis CML cells using adenoviral (Ad) vectors expressing a HSV-TK system under dua...

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Detalles Bibliográficos
Autores principales:	Zu, Bailing, Shi, Yi, Xu, Min, You, Guoling, Huang, Zhenglan, Gao, Miao, Feng, Wenli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456766/ https://www.ncbi.nlm.nih.gov/pubmed/26017281 http://dx.doi.org/10.1186/s13046-015-0139-4

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