Animal Models of Interferon Signature Positive Lupus

Human lupus is strongly associated with a gene expression signature characterized by over-expression of Type I interferon-regulated genes. A strong interferon signature generally is not seen in the standard mouse models of lupus, despite considerable evidence for the involvement of toll-like recepto...

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Detalles Bibliográficos
Autores principales: Zhuang, Haoyang, Szeto, Christopher, Han, Shuhong, Yang, Lijun, Reeves, Westley H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456949/
https://www.ncbi.nlm.nih.gov/pubmed/26097482
http://dx.doi.org/10.3389/fimmu.2015.00291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456949/
https://www.ncbi.nlm.nih.gov/pubmed/26097482
http://dx.doi.org/10.3389/fimmu.2015.00291

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